Lectin affinity electrophoresis in a yolk sac tumour in the vagina with yolk sac tumour-type glycoform of alpha fetoprotein.

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Lectin affinity electrophoresis in a yolk sac tumour in the vagina with yolk sac tumour-type glycoform of alpha fetoprotein.

AIMS To investigate a potential diagnostic use of alpha fetoprotein (alpha FP) isoform analysis by lectin affinity electrophoresis to distinguish between endodermal sinus tumours arising in the vagina in infants from those at other sites. METHODS alpha FP in the serum of a patient with a vaginal endodermal sinus tumour was analysed for its isoforms by lectin affinity electrophoresis. The isof...

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YOLK SAC TUMOR OF VAGINA

   Malignant germ-cell tumors (MGCT) are rare tumors of childhood accounting for less than 3% of pediatric malignancies. Endodermal sinus tumor (EST) forms the most common histologic subtype of MGCT. The vagina is an extremely rare site for GCTs. An 8-month-old female was admitted with a short history of vaginal bleeding, and a mass protruding from the vagina. She was pale and a mass was palpab...

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Yolk sac tumour of the anterior mediastinum.

Two cases of yolk sac tumour involving the anterior mediastinum in two young Chinese males are described. The tumour in both patients could only be partially debulked, and they died within a few months despite multiple chemotherapy. The importance of early diagnosis, radical surgery and aggressive combination chemotherapy in prolonging the period of survival of such patients is emphasized. Seru...

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Mediastinal yolk sac tumour mimicking pericardial effusion.

In this report we present a case ofprimary yolk sac tumour of the anterior mediastinum in which two dimensional echocardiography showed an extracardiac mass simulating a large pericardial effusion. Mediastinal yolk sac tumour is a rare germ cell neoplasm affecting mainly young men.' The most common presenting symptoms are dyspnoea, cough, and chest pain.2 The prognosis is usually poor, though i...

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Yolk Sac Tumor of Vagina

Malignant germ-cell tumors (MGCT) are rare tumors of childhood accounting for less than 3% of pediatric malignancies. Endodermal sinus tumor (EST) forms the most common histologic subtype of MGCT. The vagina is an extremely rare site for GCTs. An 8-month-old female was admitted with a short history of vaginal bleeding, and a mass protruding from the vagina. She was pale and a mass was palpable ...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1997

ISSN: 0021-9746

DOI: 10.1136/jcp.50.10.856